Human genome sequencing and other omics data modalities are of
critical importance for biomedical research and the future
development of healthcare.
GHGA will provide the infrastructure to meet both the desire
to handle omics data in an open and FAIR
manner and the need to keep personal data safe and secure. Other than
other European infrastructures, as a National consortium, GHGA
will have the ability to address the legal requirements specific
to Germany, enabling German researchers to help shape future
international standards for data exchange and take on leading
roles in international research consortia.
Applicant Institution: The German Cancer Research Center DKFZ, Heidelberg
Spokesperson: Dr. Oliver Stegle
GHGA Letter of Intent
The German Human Genome-Phenome Archive, which will be federated with the EGA, and which is designed to archive and facilitate analysis of human access controlled research data from Germany, has gone live today with a pilot version, distributing research data from Heidelberg and Tübingen. We look forward to its use by human biology, genetics and disease research communities.
GHGA is tightly embedded and connected to international
infrastructures and initiatives. It will be operated as a local
node within the European
Genome-Phenome Archive (EGA) federation framework.
GHGA has a unique role within the network of federated research
data infrastructure consortia (NDFI, Nationale Forschungsdateninfrastruktur)
as it is the only consortium managing controlled/access omics data.
It aims at linking this data to other consortia, especially in
the biomedical field, and thereby become a central component of a
long-term research data management strategy within the NFDI. In
particular the coordination with NFDI4MED and NFDI4Health
will provide complementary expertise on the management and record
linkage of medical records and other non-omics data types.
GHGA is in full support of the Berlin Declaration on NFDI Cross-Cutting Topics.
Several contributors or participants of GHGA are also involved in
the NFDI proposals for NFDI4Microbiota, BERD@NDFI,
FAIRmat, NFDI4Earth, NFDI4Ing, NFDI4Text+,
NFDI4HEALTH, DataPlant, NFDI4Chem
Initially, the board of directors will be formed by:
Once GHGA starts its operations, the board will consist of elected members.
|The German Cancer Research Center Heidelberg||Oliver Stegle, Benedikt Brors, Ivo Buchhalter, Daniel Hübschmann, Martin Lablans, Peter Lichter|
|Eberhard-Karls-Universität Tübingen||Oliver Kohlbacher, Jens Krüger, Sven Nahnsen, Thomas Walter|
|University Hospital Tübingen||Holm Graessner, Nisar Malek, Stephan Ossowski, Olaf Rieß|
|Charité - Universitätsmedizin Berlin||Michael Hummel, Thorsten Schlomm|
|Technische Universität München||Julien Gagneur, Thomas Meitinger, Juliane Winkelmann|
|Europäisches Laboratorium für Molekularbiologie, Heidelberg||Oliver Stegle, Peer Bork, Wolfgang Huber, Jan Korbel|
|Max Delbrück Center for Molecular Medicine, Berlin||Dieter Beule, Uwe Ohler|
|Technische Universität Dresden||Andreas Dahl, Wolfgang E. Nagel|
|University Hospital Heidelberg||Dirk Jäger, Julio Saez-Rodriguez, Christoph Schickhardt, Eva Winkler|
|Heidelberger Akademie der Wissenschaften, Heidelberg||Fruzsina Molnár-Gábor|
|Universität zu Köln||Viktor Achter, Ulrich Lang, Susanne Motameny|
|Universitätsklinikum Schleswig-Holstein, Kiel||Philip Rosenstiel|
|Helmholtz Zentrum München||Thomas Meitinger, Annette Peters, Juliane Winkelmann|
|Deutsches Zentrum für Neurodegenerative Erkrankungen e.V., Bonn||Joachim Schultze|
|Universität des Saarlandes, Saarbrücken||Jörn Walter|
|German National Cohort, Heidelberg||---|
|EMBL-EBI - European Bioinformatics Institute, Cambridge, UK||Thomas Keane|
|CISPA - Helmholtz Center for Information Security, Saarbrücken||Mario Fritz, Ninja Marnau|
|Leibniz-Rechenzentrum, München||Stephan Hachinger|
|Helmholtz Centre for Infection Research, Braunschweig||Alice McHardy|
|National Center for Tumor Diseases, Heidelberg and Dresden||Stefan Fröhling, Hanno Glimm|
Initially, the focus of GHGA will be on the cancer and rare disease communities. Major data generators will be encouraged to deposit their data in GHGA, and community reference datasets (i.e. data likely to be used regularly in downstream analyses) will be developed. Interactions with the communities will take place in targeted workshops, and via talks and/or panel discussions at general conferences and meetings.
On a broader scale, interactions will also take place with other GHGA users, including human omics data researchers, data scientists, clinical researchers, physicians, and citizen scientists.
An important aim of GHGA is to reach out to patient representatives and the general public, to raise awareness for the value of omics research and data sharing, while addressing general concerns and questions about the safety, privacy and data ownership when using such large scale human data.
GHGA received Letters of Support from the following Institutions and Societies
Dr. Oliver Stegle (DKFZ Heidelberg)
Prof. Dr. Oliver Kohlbacher (Universität Tübingen)
Informationspflicht laut § 5 TMG.
Im Neuenheimer Feld 280
Telefon: +49 (0)6221 420
Telefax: +49 (0)6221 422995
UID-Nummer: DE 143293537
Telefon: +49 (0)6221 420
Telefax: +49 (0)6221 422995
Chairman and Scientific Director: Prof. Dr. Michael Baumann
Administrative Director: Ursula Weyrich
(address like above)
Dr. Oliver Stegle
Prof. Dr. Oliver Kohlbacher